Litsea oppositifolia is one of the species found in Indonesia and its pharmacological effects have not been well studied. Therefore, the antioxidant activity of L. oppositifolia stem extract was evaluated in human keratinocytes (HacaT cells) under H2O2-induced oxidative stress through related gene expression. The ethanol stem extract of L. oppositifolia was screened initially for its antioxidan…
Skin aging is the accumulation of cellular waste that progressively leads to a loss of structural integrity and physiological function due to intrinsic and extrinsic factors. Although intrinsic aging is inevitable, it is highly influenced by extrinsic factors, including UV radiation, tobacco smoking and pollution. These repeated exposure causes the upper dermis fibroblasts to selectively los…