Keratoconus presents a significant challenge in ophthalmology, urging effective treatment strategies to mitigate its impact on patients’ lives. This study investigates the safety and efficacy of combined therapy, utilizing rose bengal (RB) and riboflavin (RBF) for keratoconus management. Through ex vivo and in vitro experiments, significant increases in corneal stiffness and cell viability…
This research study presents a comprehensive investigation into the synthesis of carbocyclic glycosyl donors, carbocyclic nucleosides, thio-glycosyl donors, and thio-nucleosides – considered as key compounds with significant implications for the chemistry of nucleosides and glycosides. A series of organic reactions were performed for each scheme, curated to manufacture the desired target mole…