Acne is the most common skin disorder. While usually transient, severe acne would leave behind disfiguring scars. Acne could be successfully treated, but as most drugs have serious side effects while not preventing scarring, new therapeutic options are needed. Novel insights in acne pathogenesis and potential therapeutic targets could be identified by studying rare monogenetic acne-associated d…
Bisphenol S ( BPS) is a BPA analogue that is considered to be safer compared to BPA due to its higher thermal stability and lower chemical reactivity. BPS is often used as a substitute to BPA in a variety of plastics, particularly food and beverage containers, baby bottles and pacifiers and also paper products. However, like BPA, residual amounts of BPS contained in various commercial products …
Colorectal cancer (CRC) is one of the most common types of cancer happening to both men and women in all race and ages, accounting 9% of all cancer incidence worldwide. In 2018 alone, there are 1.8 million new cases and almost 900,000 deaths. Causes of CRC varies into environmental and non-modifiable factors. As for the non-modifiable factors, the most established risk is inherited genetic risk…
Malaria has been one of the concerning global health problems with 212 million recorded cases of malaria infection on 2015 and 62% mortality rates from 2000-2015. Current drugs, such as Artemisinin and Chloroquine, are reported to start developing resistance. Alongside with the increasing resistance rate, the demands for novel antimalarial drugs are also increasing. Through this study, the abil…