Inflammation is a crucial part of the immune response, involving neutrophils, the predominant white blood cells, in combating pathogens. Their recruitment is regulated during inflammation, which can lead to conditions like autoimmune diseases and cancer. This study aims to explore meso- Dihydroguaiaretic acid (MDGA) derivatives, particularly MZ47, as potential therapeutic options for neut…
This study aims to generate molecular infectious clones, incorporating reporter genes (GFP and SfCherry), for flaviviruses and noroviruses—namely, Kunjin, Zika, and Murine Norovirus (MNV). The objective is to use viral constructs for antiviral compound screening and unravel their mechanisms of action. Employing a diverse array of methods, including PCR, CPER, transfection, fluorescence, an…