Myeloid leukemia is characterized by the excessive proliferation of myeloid cells within the bone marrow. It is categorized into acute (AML) and chronic (CML) myeloid leukemia, with distinct etiologies and therapeutic complexities. The genetic heterogeneity of AML contributes to varying treatment responses, leading to a high mortality rate. One gene that has been identified as an adverse pro…
Glioblastoma is the most prevalent type of malignant brain tumor, with a fatality rate close to 100%. The failure of glioblastoma treatment is mainly attributed to the high proliferation and invasion rate of glioblastoma cells, in addition to the presence of glioblastoma stem cells, all of which are regulated by the Notch signaling pathway. Past studies have observed that the Notch signaling…