inflammation plays a crucial role in the pathogenesis of various skin conditions such as psoriasis and atopic dermatitis, primarily driven by abnormal cytokine production. This study investigates the anti-inflammatory potential of several synthetic isoflavone-modified compounds (CYR-6811k, CYR-6812l, CYR-6813m, CYR-6815o, CYR-6816p) by examining their effects on cytokine production in THP-1 …
Psoriasis is an autoimmune skin disorder that has impacted the global population from children to adults. Psoriasis is characterized by unusual proliferation of keratinocytes, leading to itchy, bleeding, scaly, and red lesions due to increased immune system activity. Existing topical treatments often result in side effects, emphasizing the necessity for advanced drug discovery in managing psori…