Thesis
Immunoinformatics Analysis of SARS-COV-2 Spike Protein Indonesian Isolates
Sars-cov-2 is a virus whose spread need to be urgently curtailed. Spike proteins were analysed for epitopes as they have been found to be the immunogens used in many new releases COVID-19 vaccine. With an indonesian vaccine-"vaccine merah putih"-still in development. it remains essential to conduct immunoinformatics research on the indonesia virus isolate to support vaccine research, especially when the vaccine developed solely contain spike protein of SARS-COV-2 to ensure good population coverage in terms of epitope recognation. MHC Class II and MHC class I epitopes from the spike proteins of four indonesian isolates of SARS-COV-2 in addition to OC43 and HKU 1 hCoV were identified.
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