Thesis

In vivo study of novel biocellulose matrices for wound healing

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In Indonesia, the wound prevalence, in general, was 8.2% during 2013, with chronic wounds that have an increasing number of cases every year. In 2019, the largest share in the wound dressing market was held by advanced wound dressings due to increased cases. Natural materials, such as biocellulose and Calophyllum inophyllum (tamanu) oil, were shown to treat wounds efficiently and hinder the growth of bacteria that cause skin infection, respectively. In this study, BC hydrogel was developed and evaluated, along with tamanu oil as a combination, through an in vivo study. Results acquired showed that the BC hydrogel was successfully produced, and it showed beneficial effects in wound healing progression through histological study, while the tamanu oil was shown to be ineffective in preventing or reducing bacterial growth in wound settings in the mice model. However, tamanu oil combined with BC hydrogel exhibited a superior effect, resulting in faster and better wound healing than BC hydrogel alone.

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Availability

Detail Information

Series Title

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Call Number

BM 21-011

Publisher

Jakarta : i3L, Jakarta., 2021

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Bacterial biocellulose
Calophyllum inophyllum oil
wound healing; in vivo study

Specific Detail Info

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Statement of Responsibility

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