Epigenetics

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The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.

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Availability

Detail Information

Series Title

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Call Number

572.865 Epi

Publisher

New York : Cold Spring Harbor Laboratory Press., 2007

Collation

x, 502 p. : ill. : ind. ; 28 cm.

Language

English

ISBN/ISSN

9780879698751

Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Epigenesis, genetic
Gene Expression Regulation

Specific Detail Info

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Statement of Responsibility

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