Thesis

Clinical Trials Antimicrobial Evaluation of Daily Roll-On Deodorant and Axilla Bacterial Identification on Male University Students in Indonesian Population

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Deodorant is a cosmetic product used to reduce bad body odor. Commercialized deodorant
products usually come with a substance that enables hiding and reduces bad body odor. A clinical trial
study was held to examine the antimicrobial activity of the daily deodorant product towards four healthy
male university students in the Indonesian population via 3 days of observation at 3 different sampling
times together with identifying the remaining bacteria from the swab treated axilla sample of all subject.
Miles-Misra and Colony Forming Unit (CFU) was used to assess the antimicrobial activity of deodorant
products while selective mannitol salt agar media and Gram Staining were used to assess the presence of
Staphylococcus spp. The antimicrobial evaluation of the deodorant product showed no significant
reduction of microbial load in the treated axilla compared to the control axilla. Instead, the deodorant is
more likely to induce microbial growth since individual CFU/mL data of some participants showed an
increase in microbial load at the treated axilla compared to control. Moreover, the identification using
MSA media followed by Gram Staining confirmed the presence of Staphylococcus spp in the treated
axillary sample which proves the deodorant unable to kill Staphylococcus spp. Moreover, following the
unexpected result of the deodorant product, an additional method to check the bioburden of three
deodorant samples using a spread plate showed no microbial bioburden was detected. Therefore, the
unexpected results were not influenced by the bioburden but some product-related and subject-related
factors may drive these results.

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Availability

Detail Information

Series Title

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Call Number

BM 22-011

Publisher

i3L, Jakarta : i3L, Jakarta., 2022

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Body malodor
Deodorant
Mannitol Salt Agar
Gram Staining
Bioburden

Specific Detail Info

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Statement of Responsibility

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Other version/related

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