Thesis
Antibacterial Activity of Phenolic Acid Extracted from Pangium edule towards Staphylococcus aureus, Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae as Foodborne Pathogen
Indonesia is a country with high biodiversity and many plants' potential for pharmaceutical
and biotechnology research. Pangium edule is one of the local Indonesian spices usually used for a
specific cuisine. Currently, there are few studies of P. edule as a food preservative agent and none on
its medicinal use. P. edule seeds contain antioxidants, alkaloids, and polyphenolic compounds, which
are known to have antimicrobial activities. Foodborne pathogens such as Staphylococcus aureus,
Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae are commonly found in street
food in Indonesia. Foodborne pathogens such as S. aureus, E. coli, S. typhimurium, and K.
pneumoniae showed antibiotic resistance. This research is another approach to utilizing P. edule
potential for medicinal purposes, especially against foodborne pathogens, by focusing on
investigating the antibacterial activity exerted specifically from a phenolic acid extracted from P.
edule seeds to target foodborne pathogens such as S. aureus, E. coli, S. typhimurium, and K.
pneumoniae. The phenolic acid was extracted from the P. edule seeds, and Kirby Bauer was used as
the method to determine the antimicrobial activity exerted by the free phenolic acid and glycoside
bound phenolic acid. In conclusion, phenolic acid extracted from Pangium edule seeds can exert
antibacterial activity toward Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, and
Salmonella typhimurium as the foodborne pathogen. Therefore, phenolic acid from P. edule seeds
can be investigated more to be used as a food preservative or pharmaceutical ingredient.
No other version available