Thesis

Molecular Characterization and Antimicrobial Susceptibility Profile of S. pneumoniae, S. pseudopneumoniae and S. mitis from Madiun, Indonesia

---

The use of antibiotics across the world in the past decade has affect the development of antibiotic resistance not only by pathogenic bacteria but also commensal bacteria. This is an alarming subject, since any infection caused by commensal bacteria which supposed to be easily treated might become a life-threatening condition. Streptococcus pseudopneumoniae is classified as Viridans Group Streptococci (VGS) which is also commensal bacteria. It is believed to exert low pathogenicity in immunocompetent host. However, recently many research has proven its pathogenicity both in humans and animal model. This subject indicates the importance of characterizing S. pseudopneumoniae isolate in Indonesia and its antimicrobial susceptibility. This study aimed to isolate S. pseudopneumoniae from healthy children under 5 years old and characterize its properties as well as its antimicrobial susceptibility profile. It was found that the prevalence of S. pseudopneumoniae among healthy children were very low. The characteristics of the isolates obtained from Madiun, Indonesia includes, medial susceptibility to optochin, insoluble in bile, negative for oxidase and catalase, as well as negative for lytA, psaA, and cpsA genes. Most of the isolates were found susceptible to all the antibiotic tested, with reduced susceptibility to tetracycline. Further isolate collection is recommended to limit bias result as well as to better understand it in a bigger picture.

---

Availability

Detail Information

Series Title

-

Call Number

BM 22-042

Publisher

i3L, Jakarta : i3L, Jakarta., 2022

Collation

-

Language

English

ISBN/ISSN

-

Classification

NONE

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

S. pseudopneumoniae
S. mitis
S. pneumoniae
viridans streptococci
molecular characterization,
antimicrobial susceptibility

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment