Thesis
Identification and Flavonoids in Ethanol-Soluble Calophyllum Inophyllum Oil from Indonesia
Natural ingredients derived from plants have been more commonly implemented in
cosmetics since they can be a ‘greener’ and ‘safer’ alternative and consumers want to avoid several
ingredients that can cause skin disorders, including fragrances, parabens, phthalates, and many
more. Calophyllum inophyllum is a plant whose oil is commonly being utilized in cosmetics. Its
utilization is due to its beneficial properties like antibacterial, antioxidant, anti-inflammatory, and
wound healing activities. The oil was fractionated with absolute ethanol to overcome some
drawbacks on its application. Phytochemical screening was performed to detect the appearance of
compounds in the plants in which quinones, tannins, and alkaloids were detected. Moreover, the
total flavonoid content and phenolic content were observed. Total flavonoid content was 6.4 mg
QE/g oils, while total phenolic content was 25.1 mg GAE/g oil. LC-MS/MS was used to identify the
flavonoids present in the oil in which calophyllolide, inophyllum B, inophyllum C, inophyllum E, and
calophyllic acid were detected.
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