Thesis

Coffee Plant Proteomics Annotation for Natural Products

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Indonesia was the fourth largest coffee producer in the world in 2014, thus it is safe to say that









Indonesians love to drink coffee. The consumption of coffee has its health benefits and its risks, one
of the risks is mostly related to cardiovascular diseases. One of the diseases is hypertension which is
considered “the silent killer” as it is a serious condition which promotes other complications and
typically has no symptoms for a period of time until it has done significant damage. Stroke is one of
the conditions that is primarily caused by hypertension. Stroke is a very serious medical condition
where the blood flow to the brain is poor, causing the death of cells within the brain. Some
medications, surgeries and other healthcare programs are capable of controlling stroke, but stroke
still remains to be the main cause of death and disability in Indonesia. Multiple studies show that
coffee consumption actually can reduce the risk of getting a stroke, by consuming between 2 to 4
cups of coffee per day. Additionally, coffee can reduce the likelihood of blood clots from forming and
is likely to alter the blood vessel physiology. Therefore, the current project will explore the possibility
of utilization of bioactive compounds other than caffeine from coffee beans that can be
implemented in a form of supplements to help in treating patients both with stroke symptoms and
during the recovery phase. Protein docking analysis is an alternative way to search and predict for
drug discovery. Through protein docking analysis we can gain information on the bioactive
compounds and their respective interactions with the target.

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Availability

Detail Information

Series Title

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Call Number

BI 22-008

Publisher

i3L, Jakarta : i3L, Jakarta., 2022

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Bioactive compounds
Coffee protein
Protein Docking Analysis
Biological Pathway

Specific Detail Info

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Statement of Responsibility

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Other version/related

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