Internship Report

Assessing the Effect of Surfactant Type in Transfersome Making on The Wound Healing Activity of Binahong Leaves (Anredera cordifolia (Ten.) Steenis.) Extract

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Wounds are defined as the occurrence of damage and/or disruption of the skin integrity,
mucous membrane, and also organ tissue which can disrupt the protective function of the epidermal
tissue. Binahong (Anredera cordifolia (Ten.) Steenis.) is one example of a plant that can and has been
used empirically to heal external wounds due to its bioactive compounds. However, there are some
limitations due to the solubility of the extract of binahong leaves which might be overcome by
encapsulating them in a transfersome that has the ability to spontaneously deliver the active
ingredients through narrow skin pores. Therefore, this study was done to assess the effect of
different types of surfactant used in the formulation of transfersome on the entrapment ability of the
transfersome and the efficacy of binahong leaf extract to heal wounds. The results obtained show
that the use of tween 80 (F2) as the surfactant was able to result in the highest entrapment
efficiency with a significant difference (p0.05) between all of the formulations
and the binahong leaf extract which acts as the control.

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Availability

Detail Information

Series Title

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Call Number

PHA 22-004

Publisher

i3L, Jakarta : i3L, Jakarta., 2022

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Wound healing
Anredera cordifolia
binahong leaves
transfersome nanoparticles
surfactants
tween 80
span 80

Specific Detail Info

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Statement of Responsibility

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Other version/related

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