Internship Report

The effects of SARS-CoV-2 mRNA vaccines towards the development of Hashimoto’s Thyroiditis disease

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he increase in the rate of vaccinations against SARS-CoV-2 has proven to be an excellent
counter against the pandemic of COVID-19, but the increase of the rate in vaccinations have
inevitably caused detrimental side effects to a small group of people who received the vaccination.
The focus of this literature review will be the autoimmune thyroid disorders which have affected a
small number of people, primarily women after the vaccination of COVID-19, specifically the
BNT162B2 mRNA variant.
Hashimoto’s thyroiditis refers to the autoimmune thyroid illness where the immune cells attack the
thyroid cells, even without the administration of mRNA vaccines, the pathogenesis of Hashimoto’s
Thyroiditis is yet to be known. Hashimoto’s Thyroiditis also belongs on one of the types of
autoimmune thyroid complications, the other more common autoimmune thyroid complication
refers to Graves’ Disease, Graves’ Disease is an autoimmune disorder that causes Hyperthyroidism
which causes the thyroid to be hyperactive while Hashimoto’s Thyroiditis refers to hypothyroidism
where the thyroid gland is underactive due to the inflammation caused by the attacking immune
cells.
The definite cause of the development of Hashimoto’s Thyroiditis in patients who have received their
vaccination is yet to be known, as there is also very little to no previous literature that supports this
statement in the first place. Most autoimmune thyroid disorders developed from the administration
of mRNA vaccines include Graves’ Disease, while some also develop Subacute thyroiditis counting
non-autoimmune thyroid disorders. Because of the limited amount of literature available, most
research papers have resorted to hypotheses that are based on the current understanding of the
theory regarding the development of Hashimoto’s Thyroiditis, which may help future researchers in
continuing the research and draw a more reliable conclusion.

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Availability

Detail Information

Series Title

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Call Number

BM 22-039

Publisher

i3L, Jakarta : i3L, Jakarta., 2022

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Hashimoto’s Thyroiditis
BNT162B2 vaccine
Dosage
IL6
Th1

Specific Detail Info

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Statement of Responsibility

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Other version/related

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