Report
THE EFFECT OF SPRAY-DRYING TOWARDS THE ADHERENCE OF PEDIOCOCCUS ACIDILACTICI TO MAMMALIAN CELLS
Probiotic is a non-pathogenic microorganism that can benefit its host. Therefore to start colonization
and increase their transit time in the gut so the probiotic can interact with the host and give health
benefits they must adhere to the intestinal epithelial cells. Bacterial adhesion is a key probiotic
property that Pediococcus acidilactici must have as a probiotic. The ability of the P. acidilactici before
and after spray drying to adhere to mammalian cells was investigated. Adhesion test and aggregation
test were performed to demonstrate that P. acidilactici even after spray drying still has the ability to
adhere to the mammalian intestinal cell. The adhesion test using human colorectal adenocarcinoma
HT-29 shows that the P. acidilactici both free cell and spray drying sample has the ability to adhere to
the mammalian intestinal epithelial cell.
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