Report

Water for Injection Hold Time Study in Room Temperature

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During the internship, the main project done is the Water for injection hold time study at room
temperature. Water for injection is a type of pure water used in pharmaceutical production that has
been treated using distillation. Water for injection is used for cleaning equipment, mixing solutions,
and validating cleaning. The study aims to investigate the condition of water for injection for a period
of 2 weeks to determine the hold time of water for injection and monitor the various parameters as
described by Farmakope Indonesia. The six parameters described as appearance, pH, conductivity,
Total organic Carbon (TOC), bioburden, and endotoxin. The results of the project revealed that the
condition of the water for injection overall is kept stable throughout the two weeks using the laminar
air flow and the sterile gloves used in sampling. However, vapors of alcohol used in the room to
sterilize equipment results in increasing levels of TOC to build up. This study helps the company to
keep up with their productivity in the events that water for injection in unavailable for a period of
time

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Availability

Detail Information

Series Title

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Call Number

EP BT012

Publisher

i3L, Jakarta : i3L, Jakarta., 2022

Collation

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Language

English

ISBN/ISSN

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Classification

EP BT012

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Water for injection
hold time
Total organic Carbon (TOC)

Specific Detail Info

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Statement of Responsibility

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Other version/related

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