Thesis
Formulation and Evaluation of Effervescent Granules of Coriandrum sativum Leaves Extract
Coriandrum sativum leaves extract was made in dosage form of effervescent granules which were
expected to have an ability in treating Alzheimer ’s disease. It is essential to obtain the optimal
formulation in order to achieve the most efficient medications. Therefore, this study aimed to
formulate effervescent granules containing coriander extract and evaluate the physicochemical
characteristics of the granules. Spray drying and wet granulation process was employed. Several
assays were performed to determine the flavonoid, phenolic, and antioxidant content of the extracts
and formulas. A significant difference in TFC and TPC was found between liquid extract and
spray-dried extract as well as F2 and F3 to F1 (p-value
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