Thesis
Formulation and Evaluation of Antioxidant Cream Containing Morinda citrifolia and Propolis Extract
Skin issues are common problems in daily life. The oxidative effect by exposure to UV radiation
and pollution causes skin inflammation and premature aging. Nowadays, the cosmetic industry
has shifted toward usage of natural products. The Noni fruit (morinda citrifolia) used as food and
medicine, prevents and treats a variety of diseases. The problem with the extract is their poor
penetration. Morinda citrifolia extract was planned to formulate into cream, to make it unique,
the extract was combined with another extract, in which the propolis extract, scientists discovered
presence of phenolic acids, esters, and flavonoids, which have high antiradical activity, is
responsible for its pharmacological activities. The objective of this study was to formulate and
evaluate antioxidant cream containing morinda citrifolia and propolis extract combination. DPPH
testing was used to check the antioxidant of the extracts, the IC50 of antioxidant activity of the
combine extract through DPPH assay was 58.34 ppm, while the propolis IC50 40.56 ppm, however
the morinda citrifolia IC50 was unstable. Nonetheless, the extract still showed a percentage of
inhibition value ranging from 48.84 - 53.96 %. The chosen concentration extract was formulated
into 3 formulation creams, while the evaluation of the cream were organoleptic, pH, emulsion
type, spreadability, centrifugation, viscosity, and sensory test. The result of the evaluation showed
that the physical conditions have good color, smell, however the texture of the cream is too
viscous, due to its high amount of emulsifying agent, other evaluation results mostly considered
the cream still safe and follow the standard of the evaluation. Overall from 3 formulations, formula
3 gave best result mostly on the evaluation, however the overall liking from the sensory testing
shows formula 1 was preferred as the best choice from all 3 formulations
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