Internship Report

Evaluation of Delayed and Reversible Toxicity of Repeated Fennel (Foeniculum vulgare) Extract Administration in Mice

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This subchronic toxicity study assessed the delayed toxicity and reversibility of fennel extract in male and female mice. To ascertain any delayed toxicity and potential for recovery, a separate satellite group received oral doses of fennel extract at a dose of 1000 mg/kg/day of body weight for a duration of 90 days, followed by 28-days with no treatment. There were no abnormalities observed in the satellite group’s weight and biochemical parameters when compared to the control group. The findings indicate that fennel extract at a dose of 1000 mg/kg/day of body weight did not cause delayed oral subchronic toxicity in both male and female mice.

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Detail Information

Series Title

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Call Number

PHA 23-013

Publisher

i3L, Jakarta : i3L, Jakarta., 2023

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

subchronic toxicity
Fennel (Foeniculum vulgare) extract
Delayed toxicity
Reversibility
Biochemical parameters

Specific Detail Info

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Statement of Responsibility

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