Thesis

In Vitro Assessment of a Deodorant’s Antibacterial Efficacy On Corynebacterium Tuberculostrearicum And Staphylococcus Hominis

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"The human axilla hosts clusters of sweat glands that provide a favorable environment for a
large bacterial population. The bacteria-driven process could convert the odorless secretions from
the glands into volatile odorous compounds, leading to an unpleasant body odor that may disrupt
people’s daily routines. To address this issue, the development of cosmetics like deodorant has the
potential to reduce or eliminate the growth of odor-producing bacteria in the human axilla.
Deodorants are typically formulated to include various antibacterial ingredients that effectively
inhibit the growth of odor-causing bacteria and neutralize the odor itself. Hence, this research will
evaluate the antimicrobial effectiveness of a newly formulated deodorant against axillary bacterial
culture through in vitro settings. The study involved measuring optical density (OD), utilizing the
Miles and Misra technique, measuring the zone of inhibition (ZOI) using a spot plating assay, and
conducting a time-kill assay. The findings indicated a higher growth rate of C. tuberculostearicum
compared to S. hominis. The deodorant-to-bacterium ratio test showed that Deodorant X exhibited
superior antibacterial activity with most favorable outcome at 0.25:1 ratio against both C.
tuberculostearicum and S. hominis. Moreover, the spot plating assay revealed a greater ZOI for
Deodorant X against both bacterial samples. Additionally, the time-kill assay also demonstrated that
both Deodorant X and Rexona exerted bacteriostatic effects. Therefore, the in vitro assessment can
be employed to evaluate the antibacterial effects of deodorant against human axillary-isolated
microbes, particularly C. tuberculostearicum and S. hominis.
Keywords: Axilla; Body odor; Deodorant; Bacterial growth; Antibacterial"

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Availability

Detail Information

Series Title

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Call Number

EP BM-022

Publisher

i3L, Jakarta : i3L, Jakarta., 2024

Collation

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Language

English

ISBN/ISSN

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Classification

EP BM-022

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Axilla
Antibacterial
Deodorant
Body odor
bacteria

Specific Detail Info

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Statement of Responsibility

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