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Lineage Tree: Visualization Platform for Exploring SARS-CoV-2 Pango Lineage Networks and Lineage-Defining Mutations

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Public health surveillance plays a pivotal role in ending the COVID-19 emergency, especially monitoring
the emergence of new lineages. A dynamic SARS-CoV-2 lineage naming system, known as the Pango
nomenclature system currently being used to assist genomic epidemiology. Currently, researchers
manually draw charts to visualize mutations found in major pango lineages that shape the evolutionary
paths of SARS-CoV-2 and there is no automated pipeline to produce these visualizations. This study
proposes a system to strengthen the monitoring and tracking of SARS-CoV-2 by utilizing datasets from
Pango-lineage designations and the GISAID EpiCoV database that eliminates the tedious and manual
methodology. In addition, information regarding the mutations that uniquely define the lineage and
mutations that are shared with the immediate lineage parent could benefit researchers such as those
interested in designing new vaccines against the newly mutated SARS -CoV-2 viruses.

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Availability

Detail Information

Series Title

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Call Number

BI 24-002

Publisher

i3L, Jakarta : i3L, Jakarta., 2024

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

SARS-COV-2
virus lineage
visualization
lineage-defining mutations
shared-parental mutations

Specific Detail Info

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Statement of Responsibility

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