Thesis
Personalized Medicine Using Next Generation Sequencing (NGS) from Doctor’s Perspective: Qualitative Approach
Personalized medicine helps make decisions about illness prevention, diagnosis, and
therapy based on a person's genetic profile. To use personalized medicine, genetic testing
using Next generation sequencing (NGS) performed to determine the best drugs to treat the
diseases. Cancer can be treated using personalized medicine. Each year, the number of
cancer patients is rising, and with personalized medicine, the patients can be treated using
the right medicine faster. However, there are many factors that halt the use of this
technology to treat cancer in Indonesia. Thus, the aim of this research is to find and validate
the factors that affect doctors and cancer patients in Indonesia who are reluctant to use
personalized medicine. Also, to find some solutions to make personalized medicine more
accessible in Indonesia based on the factors gathered from the doctors. This research will
use qualitative methods (In-depth interview) with several doctors to collect information
about personalized medicine for cancer and define the factors that make doctors hesitant to
suggest personalized medicine. The result shows high cost, lack of knowledge, duration of
testing, availability of the drugs and facilities, and lack of support from the government are
the factor that influence the doctors and patients reluctant in using personalized medicine
in Indonesia. Some suggestion include funding institutions to do research about
personalized medicine, opening NGS testing facilities throughout Indonesia, and also
broaden the genetic panels to test the sample. Limitations of this study are that the result
only based on a few doctors who share their knowledge.
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