Thesis

Fractionation and Characterization of Compounds from Potentially Antiviral Laportea decumana (Daun Gatal) Leaf Methanolic Extract against Influenza

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The search for potential antiviral compounds in scientific research has emerged as a key target in
battling against a global health threat from diverse infectious diseases. Daun gatal, also known as
Laportea decumana, is a traditional native plant known for its pain relieving properties. Despite its
unassuming nature, Daun gatal offers an abundant quantity of phytochemicals that indicate the
presence of antiviral properties. In this research, Daun gatal leaves methanolic extract was prepared
and underwent phytochemical screening. The antiviral properties of the extract was then determined
through in vitro activity assay. The outcome of the assay led to further purification of the extract.
Several fractions were obtained and subjected to further characterization through IR spectroscopy,
UV-Vis spectrophotometry, and LC-MS/MS. This study showed that Daun gatal leaves methanolic
extract exerts antiviral properties against MDCK cell lines, which serves as the basis for further
research in addressing novel antiviral therapies, particularly in combating Influenza A virus.

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Availability

Detail Information

Series Title

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Call Number

PHA 24-017

Publisher

i3L, Jakarta : i3L, Jakarta., 2024

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Antiviral
Influenza A virus
Daun gatal (Laportea decumana)
Characterization

Specific Detail Info

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Statement of Responsibility

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