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The Properties of Daun Dewa as Antiviral Compound

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The demand for continuous discovery of novel antimicrobial compounds is still very
high, especially considering the pandemic the world has recently faced. Many types of
antimicrobials can be found in natural ingredients and the vast biodiversity of Indonesia
certainly holds many natural compounds that have the potential to be a new novel
antimicrobial compound. Gynura divaricata, or also known as Daun Dewa in Indonesia, has
been hypothesized to have antimicrobial properties because of its flavonoids that is known to
ease illnesses such as respiratory tract infections and digestive disorders as well. The
assessment of G. divaricata antiviral activity was done using plaque assay where the
formation of plaques upon the administration of G. divaricata Extract is observed, and the
expression of inflammatory genes through the assessment of qRT-PCR. Upon the results
observation G. divaricata has shown a strong antiviral activity towards the treated cells and
helps with lowering the overall cell death upon the administration of infected cells. Proving
that the activity of G. divaricata in antiviral assays, however, as the qRT-PCR experiment
failed to show any reliable results, the plant extract’s potency in reducing the overall
anti-inflammatory response needs to be studied further in future experiments.

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Availability

Detail Information

Series Title

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Call Number

BM 24-044

Publisher

i3L, Jakarta : i3L Press., 2024

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Gene Expression
Gynura divaricata
antiviral activity
plaque inhibition

Specific Detail Info

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Statement of Responsibility

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