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The Properties of Daun Dewa as Antiviral Compound

Sultan Syarief Abdullah - Personal Name;

The demand for continuous discovery of novel antimicrobial compounds is still very
high, especially considering the pandemic the world has recently faced. Many types of
antimicrobials can be found in natural ingredients and the vast biodiversity of Indonesia
certainly holds many natural compounds that have the potential to be a new novel
antimicrobial compound. Gynura divaricata, or also known as Daun Dewa in Indonesia, has
been hypothesized to have antimicrobial properties because of its flavonoids that is known to
ease illnesses such as respiratory tract infections and digestive disorders as well. The
assessment of G. divaricata antiviral activity was done using plaque assay where the
formation of plaques upon the administration of G. divaricata Extract is observed, and the
expression of inflammatory genes through the assessment of qRT-PCR. Upon the results
observation G. divaricata has shown a strong antiviral activity towards the treated cells and
helps with lowering the overall cell death upon the administration of infected cells. Proving
that the activity of G. divaricata in antiviral assays, however, as the qRT-PCR experiment
failed to show any reliable results, the plant extract’s potency in reducing the overall
anti-inflammatory response needs to be studied further in future experiments.


Availability
#
Reference Collection (BM Thesis) BM 24-044
T202409058
Available
Detail Information
Series Title
-
Call Number
BM 24-044
Publisher
i3L, Jakarta : i3L Press., 2024
Collation
-
Language
English
ISBN/ISSN
-
Classification
NONE
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Gene Expression
Gynura divaricata
antiviral activity
plaque inhibition
Specific Detail Info
-
Statement of Responsibility
-
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No other version available

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Indonesia International Institute for Life Sciences - Learning Resources Center
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i3L Learning Resources Center (LRC) is vital part of your academic experience at Indonesia International Institute for Life-Sciences. LRC exists to support the teaching, learning and research programs of the Institute through the provision of high quality services and facilities which include access to a range of printed and digital resources primarily in the field of life-sciences and business. 

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