Thesis

Formulation and Evaluation of Wound Healing Properties of the Moringa oleifera lam. leaf Extract and Allantoin-Based Anti-Acne Serum

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Preventing severe acne manifestations necessitates early intervention, primarily through reducing
inflammation and accelerating wound healing. Facial serums with natural ingredients are increasingly
popular due to their minimal side effects and cost-effectiveness, while offering significant potential in
acne treatment. Moringa oleifera lam. leaf extract and allantoin are individually recognized for their
wound healing properties. This study explores the combined effects of these agents on wound
healing using the scratch assay method. The optimal combination of 12.5 ppm allantoin and 50 ppm
Moringa oleifera demonstrated higher wound healing rate compared to individual applications and
the control group. This optimal combination was successfully incorporated into a facial serum gel
formulation, exhibiting favorable physicochemical properties, stability, and user acceptance. These
findings suggest that a facial serum incorporating 12.5 ppm allantoin and 50 ppm Moringa oleifera
could be an effective approach for acne treatment through enhanced wound healing and reduced
inflammation. Further investigation is warranted to validate these results and explore the underlying
mechanisms.

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Availability

Detail Information

Series Title

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Call Number

PHA 24-016

Publisher

i3L, Jakarta : i3L Press., 2024

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Wound healing
Moringa oleifera lam
leaf extract
Allantoin
Facial Serum Formulation

Specific Detail Info

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Statement of Responsibility

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Other version/related

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