Biostatistical methods : the assessment of relative risks

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Biostatistics consists of various quantitative techniques that are essential to the description and evaluation of relationships among biologic and medical phenomena. Biostatistical Methods: The Assessment of Relative Risks, Second Edition develops basic concepts and derives an expanded array of biostatistical methods through the application of both classical statistical tools and more modern likelihood-based theories. With its fluid and balanced presentation, the book guides readers through the important statistical methods for the assessment of absolute and relative risks in epidemiologic studies and clinical trials with categorical, count, and event-time data.

Presenting a broad scope of coverage and the latest research on the topic, the author begins with categorical data analysis methods for cross-sectional, prospective, and retrospective studies of binary, polychotomous, and ordinal data. Subsequent chapters present modern model-based approaches that include unconditional and conditional logistic regression; Poisson and negative binomial models for count data; and the analysis of event-time data including the Cox proportional hazards model and its generalizations. The book now includes an introduction to mixed models with fixed and random effects as well as expanded methods for evaluation of sample size and power. Additional new topics featured in this Second Edition include: * Establishing equivalence and non-inferiority * Methods for the analysis of polychotomous and ordinal data, including matched data and the Kappa agreement index * Multinomial logistic for polychotomous data and proportional odds models for ordinal data * Negative binomial models for count data as an alternative to the Poisson model * GEE models for the analysis of longitudinal repeated measures and multivariate observations

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Availability

Detail Information

Series Title

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Call Number

519.5 Lac b

Publisher

Hoboken, NJ : Wiley., 2011

Collation

xxiii, 622 p. : ill. : ind. ; 25 cm.

Language

English

ISBN/ISSN

9780470508220

Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

2nd

Subject(s)

Biostatistics.

Specific Detail Info

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Statement of Responsibility

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