The worldwide impact of breast cancer (BRCA) has received a lot of attention due to its poor prognosis which leads to the high mortality and morbidity rate. Studies suggest that the high morbidity rate is mainly due to ineffectiveness of existing conventional therapies including chemotherapy, surgery as well as radiation therapy. Consequently, researchers are investigating gene therapy as a pro…
This internship program at PT Ramuraga Tirta Lestari aimed to optimize and improve various aspects of kombucha production, including food safety, data organization, and production efficiency. The intern worked on several projects to achieve this goal, such as calibrating pH meters to ensure accurate measurement of acidity levels in kombucha, sterilizing bottles to prevent contamination and main…
Staphylococcus aureus (SA) is an opportunistic human pathogen that can cause infections in humans, including atopic dermatitis, also known as eczema. Eczema is a skin condition where patients experience flare-ups characterized by redness, itchiness, dried skin, and may vary among individuals. Interestingly, there is a common pattern where all eczema patients' skin is colonized by SA, and treatm…
Mahidol University is one of the best Campuses in Thailand, which focused on science and medicine. Organic chemistry is part of the department that mainly focuses on the synthesis of natural compounds as well as finding new synthetic methods that are more effective. In this internship oppurtunity, the author got a chance to experience how to work as a chemist. Specifically, this internship proj…
Unsupervised machine learning as a part of machine learning is an algorithm that identifies available information without any guidance or supervision in a form of clustering. When producing clustering analysis, obtaining optimized data is crucial. Missing values, zero values, inappropriate data input and outliers can affect the overall analysis of the dataset. Data cleaning tools in the data cl…
Skin Cutaneous Melanoma (SKCM) is one of the combative cancers due to the higher estimation in diagnosis case and melanoma deaths between 2020 and 2040. The lack of early management has become the major factor hence the past few years' scientists have been studying the skin cutaneous melanoma using bioinformatics analysis to examine DEGs,generate the risk prediction model and proposing the …
Development of Drugs provide specific information on drug targets, mechanism, and interaction with other drugs. This information is important in order to prevent adverse drug reactions when prescribing more than 1 drugs. Electonic databases like Drugbank provide stotrage and access of this information to the public mass. However, not all drug databases are freely available making it hard to aut…
Assistive technology (AT) is invaluable to people with special educational needs and disabilities, enabling them to function more efficiently. Designed with low power consumption and a GPU capable of running AI frameworks, NVIDIA's Jetson Nano is an affordable embedded system device. With this system, users will be mobile and connected to any computer with an appropriate interface, and able…
PT Meprofarm is a pharmaceutical company founded in 1973 by Bapak Ir. Wanne Mardiwidyo. In the time of the internship, there are 2 main buildings, MEPRO-1 and MEPRO-2. Research and development department falls under the Manufacturing department, which is one of four main departments in PT Meprofarm. Research and development team focuses on drug development, one of the divisions is the new p…
Exploratory data analysis helps to recognize natural patterns hidden in the data. This book describes the tools for hypothesis generation by visualizing data through graphical representation and provides insight into advanced analytics concepts in an easy way. The book addresses the complete data visualization technologies workflow, explores basic and high-level concepts of computer science and…
Showing you how to take a structured and organized approach to a wide range of literature review types, this book helps you to choose which approach is right for your research. Packed with constructive tools, examples, case studies and hands-on exercises, the book covers the full range of literature review techniques. New to This Edition: Full re-organization takes you step-by-step through …
Storytelling with Data teaches you the fundamentals of data visualization and how to communicate effectively with data. You'll discover the power of storytelling and the way to make data a pivotal point in your story. The lessons in this illuminative text are grounded in theory, but made accessible through numerous real-world examples—ready for immediate application to your next graph or pres…
Logic and Critical Thinking in the Biomedical Sciences: Volume I: Deductions Based upon Simple Observations provides biomedical students and scientists with a repertoire of deductive non-mathematical methods, that helps them draw useful inferences from their own data. The past decade has witnessed a huge increase in the number of books describing advanced mathematical methods for data analysis;…
Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that teaches students th…
Practical Bioinformatics is specifically designed for biology majors, with a heavy emphasis on the steps required to perform bioinformatics analysis to answer biological questions. It is written for courses that have a practical, hands-on element and contains many exercises (for example, database searches, protein analysis, data interpretation) to complement the straightforward and practical to…
Reflecting new software updates, and with more advanced topics, the Fourth Edition helps the student create phylogenetic trees from protein or nucleic acid sequence data. The reader is taken step-by-step from identifying the sequences required, to drawing the tree for presentation to an intended audience.
The Phylogenetic Handbook is a broad, hands on guide to theory and practice of nucleotide and protein phylogenetic analysis. This second edition includes six new chapters, covering topics such as Bayesian inference, tree topology testing and the impact of recombination on phylogenies, as well as a detailed section on molecular adaptation. The book has a stronger focus on hypothesis testing than…
DNA microarrays have revolutionized molecular biology and are becoming a standard tool in the field. Dov Stekel's book is a comprehensive guide to the mathematics, statistics, and computing required to use microarrays successfully. Unlike traditional molecular biology, the successful use of DNA microarrays requires the application of statistics and computing to design the arrays and experiments…
Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collect…
Computers have become an essential component of modern biology. They help to manage the vast and increasing amount of biological data and continue to play an integral role in the discovery of new biological relationships. This in silico approach to biology has helped to reshape the modern biological sciences. With the biological revolution now among us, it is imperative that each scientist deve…
This fully revised version of a world-renowned bestseller provides readers with a practical guide covering the full scope of key concepts in bioinformatics, from databases to predictive and comparative algorithms. Using relevant biological examples, the book provides background on and strategies for using many of the most powerful and commonly used computational approaches for biological discov…
One of the most pressing tasks in biotechnology today is to unlock the function of each of the thousands of new genes identified every day. Scientists do this by analyzing and interpreting proteins, which are considered the task force of a gene. This single source reference covers all aspects of proteins, explaining fundamentals, synthesizing the latest literature, and demonstrating the most im…
As more species' genomes are sequenced, computational analysis of these data has become increasingly important. The second, entirely updated edition of this widely praised textbook provides a comprehensive and critical examination of the computational methods needed for analyzing DNA, RNA, and protein data, as well as genomes. The book has been rewritten to make it more accessible to a wider au…
Covering theory, algorithms, and methodologies, as well as data mining technologies, Data Mining for Bioinformatics provides a comprehensive discussion of data-intensive computations used in data mining with applications in bioinformatics. It supplies a broad, yet in-depth, overview of the application domains of data mining for bioinformatics to help readers from both biology and computer scien…
Most life science researchers will agree that biology is not a truly theoretical branch of science. The hype around computational biology and bioinformatics beginning in the nineties of the 20th century was to be short lived (1, 2). When almost no value of practical importance such as the optimal dose of a drug or the three-dimensional structure of an orphan protein can be computed from fundame…
Hugely successful and popular text presenting an extensive and comprehensive guide for all R users The R language is recognized as one of the most powerful and flexible statistical software packages, enabling users to apply many statistical techniques that would be impossible without such software to help implement such large data sets. R has become an essential tool for understanding and carry…