The demand for continuous discovery of novel antimicrobial compounds is still very high, especially considering the pandemic the world has recently faced. Many types of antimicrobials can be found in natural ingredients and the vast biodiversity of Indonesia certainly holds many natural compounds that have the potential to be a new novel antimicrobial compound. Gynura divaricata, or also kn…
Pasta is one of the most popular staple foods for many consumers. Colored pasta has emerged as a creative approach to improve product appearance. Red Fruit Oil (RFO) (Pandanus conoideus Lam) can serve as natural colorants with potential health benefits. Encapsulation method using spray drying was applied to RFO to lower the susceptibility and mask unpleasant sensory profiles. This project a…
Nepenthes truncata is an endangered ornamental plant that has increasing demands due to its exotic look, commercial value and various medicinal properties. Previously, INAGRO has attempted to subculture and preserve the N. truncata but did little to no avail, although other nepenthes available in the institution were able to grow well in the same media. Some N. truncata explants even ha…
Cocoa is widely used as a raw ingredient in both confectionery and non-confectionery products in the food industry. In the food industry, the most commonly used cocoa derivatives product is cocoa powder. In this project, cocoa powder would be used as one of the ingredients inside the chocolate cream filling. There would be one control sample and three prototypes of cream filling with the reduct…
Malaria is one of the world’s most prominent and life-threatening parasitic diseases which spreads through bites of infected female Anopheles mosquitoes. Moreover, due to the increase of resistance to the current antimalarial drug as well as the high mutation rate of this parasite, there is a tendency and preference of herbal plants usage as treatment medicine which open further possible …
Immunomodulators refer to any substance that can promote or modulate immune function. The idea of immunomodulators has become increasingly significant around the world as people began to understand how essential the immune system is to preserve a healthy individual. There are various synthetic drugs used as immunomodulators. However, due to several adverse effects, people now prefer to util…
Gynura divaricata has been widely used as traditional Chinese medicine for treating a variety of diseases. The bioactive compounds of G. divaricata, especially its rich flavonoid and phenolic acid contents make the plant has potential to be used as an antimalarial. In order for a substance to be used as an antimalarial, it needs to have low toxicity against human cell…
Immunomodulatory effect can be defined as the changes of immune response to the normal level. One of the sources of immunomodulator is herbal medicine. Traditional herbal medicine are receiving a lot of attention in human health nowadays, one of the reasons is because they are believed to have immunomodulatory activity. Gynura divaricata is a popular Asian herb that is commonly used as an alter…
Malaria is a parasitic infection affecting people worldwide, with P. falciparum being the most dangerous. Identifying more validated asexual and sexual blood-stage drug targets may be key to malaria eradication and control for a variety of reasons. Gynura divaricata (Lour.) Merr. is an Indonesian medicinal herb that contains various natural compounds with antibacterial and potentially antim…
Adverse effects of first-line drugs used for colorectal cancer (CRC) therapy have been persisting as one of the problems in CRC treatment strategies. Drug repurposing is a method that utilizes approved or investigational drugs that were initially not intended for cancer therapy as an alternative treatment. Simvastatin, a HMG-CoA reductase inhibitor, and ethyl extracts of Annona muricata leaves …
RNA technologies are the driving forces of modern medicine and biotechnology. They combine the fields of biochemistry, chemistry, molecular biology, cell biology, physics, nanotechnology and bioinformatics. The combination of these topics is set to revolutionize the medicine of tomorrow. After more than 15 years of extensive research in the field of RNA technologies, the first therapeutics are …