Cervical cancer (CC) is one of the most prevalent malignancies in females worldwide, in which one of its major causative agents is human papillomavirus type 16 (HPV16). The current HPV screening measures are responsible for reducing CC incidence; however, some limitations still persist which brings about the necessity to investigate novel biomarkers. The HPV16 genome contains several genes with…
The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illum…
Anomalous epigenetic patterns touch many areas of study including biomedical, scientific, and industrial. With perspectives from international experts, this resource offers an all-inclusive overview of epigenetics, which bridge DNA information and function by regulating gene expression without modifying the DNA sequence itself. Epigenetics, in its most basic form, means heredity is not the so…