Alzheimer’s disease (AD) is a chronic neurodegenerative disease affecting cognition and memory. The exact cause of AD remains unclear, but two primary theories have been suggested to explain its cause: the cholinergic and amyloid hypothesis. The extracellular deposition of amyloid-beta (Aβ) and intracellular accumulation of phosphorylated tau protein called neurofibrillary tangles (NFTs) …
"Alzheimer’s Disease (AD) is most common form of dementia and a neurodegenerative disease characterized by significant decline in cognitive ability that interferes with daily activities. This disease is characterized by accumulation of amyloid-β, NFTs, and oxidative stress in the brain of AD patient that leads to inflammation and neurotoxicity. Around 50 million people worldwide suffer from …