This study aims to generate molecular infectious clones, incorporating reporter genes (GFP and SfCherry), for flaviviruses and noroviruses—namely, Kunjin, Zika, and Murine Norovirus (MNV). The objective is to use viral constructs for antiviral compound screening and unravel their mechanisms of action. Employing a diverse array of methods, including PCR, CPER, transfection, fluorescence, an…
Zika virus is a mosquito-borne Flavivirus and is additionally transmitted by sexual contact, across the placenta and by blood transfusion. The spread of the Zika virus is also of concern in Indonesia, considering that Indonesia is a tropical country and an endemic area for dengue fever every year. There is currently no vaccine available to protect against or drug to treat Zika virus infect…