Cognition is an individual’s ability to learn, solve, and appropriately use stored information. Cognitive deficits can manifest in various ways and are commonly caused mainly by age, and other health conditions such as neurodegenerative diseases as well as side effects from certain drugs. Currently, natural supplements using herbal plants have been investigated as cognitive enhancers and b…
The expression of progerin, a mutated form of lamin A protein, is caused by autosomal dominant mutation in the LMNA gene. It is located in the nuclear lamina of the cells, and can affect the overall cell structure, especially in skeletal muscle cells (myocytes), in which central nucleation can occur. In order to detect the effects of progerin in the cells’ morphology, there are several techni…
Lamins are the major component of nuclear lamina that have roles in several cellular processes, such as cell proliferation and cell survival. Especially lamin B1, which plays a role in maintaining mechanical support of the nucleus, is believed to be essential during embryo development for proper organogenesis. However, previous research has discovered the correlation between age-related kidney …