Oral Squamous Cell Carcinoma (OSCC) is one of the leading malignant tumors worldwide. The oncogenic long non-coding RNA (IncRNA), LncX, was reported to play a critical role in OSCC progression. To further identify and characterize the key pathways and genes downstream of LncX, we will integrate online datasets and bioinformatic analysis to investigate the expression pattern of LncX in OSCC and …
Pancreatic ductal adenocarcinoma (PDAC) is characterized by poor prognosis, being commonly diagnosed in the unresectable advanced or metastatic stage which poses an extremely poor prognosis for patients. Hypoxia predominates most pancreatic cancer tumour microenvironments (TME), with HIF-1 signalling being overexpressed in 88% of all pancreatic cancers. Long noncoding RNAs (lncRNAs) have emerge…
Prostate cancer (PC) is a heterogeneous disease that has a slow progression compared to other types of cancers, where the severity of prostate cancer commonly increases along the age of each individual. PC is still considered as a global disease and its development is affected by racial differences. African-American (AA) men are proven to be more susceptible to PC compared to European-Ame…