Malaria remains a significant public health challenge despite advancements in treatment and prevention. The interaction between the malaria parasite and human red blood cells (RBCs) leads to the evolution of RBC disorders that offer protection against malaria. This study aimed to determine the prevalence of RBC disorders from archived DNA samples collected from malaria-endemic and non-endem…
Malaria, a global health concern, recorded approximately ÃÅÂ million cases and ÇÃÈ,ÁÁÁ deaths in ÃÁÃÁ, with Southeast Asia ranking second in malaria cases Understanding the age structure of mosquito populations is crucial for comprehending malaria transmission dynamics and assessing the impacts of environmental changes and control measures Combating malaria involves control pro…
Malaria is a major health issue worldwide, with Papua being the epicenter of malaria in Indonesia. To reduce malaria transmission, diagnostic methods have become a crucial pillar in malaria control and elimination. Due to their simplicity, rapid diagnostic tests (RDTs) are used to diagnose malaria in areas lacking expert microscopists, specifically PfHRP2-based RDTs. However, the emergence …
Malaria is a disease caused by infection of the Plasmodium parasite that spreads through Anopheles mosquitoes, which mainly plagues humans living in regions with poor healthcare and countries around the equator. Among the five species capable of causing malaria in humans, Plasmodium falciparum and Plasmodium vivax are noted as the most threatening species, as their manifestations in humans …
Malaria is an infectious illness caused by Plasmodium parasites and vectored by Anopheles mosquitoes. Recent developments in genetic engineering have opened the doors to paratransgenesis as a technique to combat malaria. This preliminary in silico project aims to investigate an unorthodox paratransgenic approach to eliminating Plasmodium cells in the mosquito. A recombinant Ti plasmid, inte…
Malaria has been a major health issue in Indonesia. Thus, diagnostic methods play a major role in the control and elimination of the disease. The most common methods in the field to detect malaria are microscopy and rapid diagnostic test (RDT), with the latter more recommended due to its simplicity and minimal expertise requirements. The most widely used RDTs are PfHRP2-based RDTs. However, the…
This study explores the research that was carried out in Jakarta, Indonesia at the Indonesia International Institute for Life Sciences (i3L). The problem of drug-resistant forms of the malariacausing parasite Plasmodium falciparum in Indonesia is the main topic of this report. The study emphasizes the necessity of developing new diagnostic techniques in order to quickly and accurately detect dr…
Malaria is one of the world’s most prominent and life-threatening parasitic diseases which spreads through bites of infected female Anopheles mosquitoes. Moreover, due to the increase of resistance to the current antimalarial drug as well as the high mutation rate of this parasite, there is a tendency and preference of herbal plants usage as treatment medicine which open further possible …
Malaria is a parasitic infection affecting people worldwide, with P. falciparum being the most dangerous. Identifying more validated asexual and sexual blood-stage drug targets may be key to malaria eradication and control for a variety of reasons. Gynura divaricata (Lour.) Merr. is an Indonesian medicinal herb that contains various natural compounds with antibacterial and potentially antim…