Mycobacterium tuberculosis samples were sequenced by whole-genome sequencing and the data were analyzed using Galaxy. The bad sequence from the raw data was trimmed and then the SNPs were compiled using Snippy. The mutation in the samples according to the reference genome was compiled into a TB profile report and then further compiled into one single file. Almost all results of the galaxy f…
Tuberculosis caused by an obligate aerobic bacteria known as Mycobacterium tuberculosis is one of the most lifelong diseases that has been infecting humans worldwide; Indonesia is one of the countries that has the highest prevalence of tuberculosis. The bacteria itself possesses an atypical cell wall structure that protects them from harmful drugs. With the inconsistent, prolonged drug treatmen…
Tuberculosis for a long period of time has become part of the cause for the mortality rate that burdened numerous patients around the world. Not only physically but also socioeconomically burdened the patient due to the long period of the regimen that the patient has to put through. Nevertheless, recent vaccine candidates for tuberculosis now have been researched that are said to be better able…
"Multi-drug resistant tuberculosis (MDR-TB) is a disease caused by the Mycobacterium tuberculosis that could evade at least two different first-line anti tuberculosis drugs. MDR-TB poses a significant global health challenge, particularly in middle to lower income countries where affordable and rapid diagnostic tools are crucially needed. This situation has brought the idea of leveraging who…
Tuberculosis is a disease caused by Mycobacterium tuberculosis which mainly attacks the lung but could also cause disease in other organs such as lymphatic system, bone, skin and liver. According to WHO, Indonesia is ranked second in total tuberculosis per year in the w orld. C urrently tuberculosis is handled in Indonesia with medication regimen to cure the disease and BCG vaccination in child…