The COVID−19 pandemic has been going on for three years, and research on preventive and curative measures is continuously being made. Belonging to the same coronavirus family, human common cold coronaviruses (CCCs) like 229E, NL63, HKU1, and OC43 have been around for decades. However, unlike SARS−CoV−2, they do not manifest serious signs and symptoms. Reports on T−cell cross−reactivit…
Nowadays, the various variants of SARS-CoV-2 have been found along with the time. It has been marked down that the antigenic drift takes a part of those occurrences. In genome mapping, SARS-CoV-2 has the largest Open Reading Frame (ORF) called ORF1ab which translates 16 different Non-Structural Protein (NSP) for viral replication. This project aims to predict the conservancy of the ORF1ab d…