Mycobacterium tuberculosis samples were sequenced by whole-genome sequencing and the data were analyzed using Galaxy. The bad sequence from the raw data was trimmed and then the SNPs were compiled using Snippy. The mutation in the samples according to the reference genome was compiled into a TB profile report and then further compiled into one single file. Almost all results of the galaxy f…
Tuberculosis caused by an obligate aerobic bacteria known as Mycobacterium tuberculosis is one of the most lifelong diseases that has been infecting humans worldwide; Indonesia is one of the countries that has the highest prevalence of tuberculosis. The bacteria itself possesses an atypical cell wall structure that protects them from harmful drugs. With the inconsistent, prolonged drug treatmen…
Tuberculosis for a long period of time has become part of the cause for the mortality rate that burdened numerous patients around the world. Not only physically but also socioeconomically burdened the patient due to the long period of the regimen that the patient has to put through. Nevertheless, recent vaccine candidates for tuberculosis now have been researched that are said to be better able…
"Multi-drug resistant tuberculosis (MDR-TB) is a disease caused by the Mycobacterium tuberculosis that could evade at least two different first-line anti tuberculosis drugs. MDR-TB poses a significant global health challenge, particularly in middle to lower income countries where affordable and rapid diagnostic tools are crucially needed. This situation has brought the idea of leveraging who…
(TB) is a disease caused by Mycobacterium tuberculosis. According to WHO 2020 data, Indonesia is one of the countries with a high number of TB sufferers, highlighting the importance of accessible TB treatment. Additionally, starting in 2021, the Department of Health of the Republic of Indonesia announced that Indonesia aims to be TB-free by 2030. TB is traditionally treated using Isoniazid, Rif…
Tuberculosis (TB) is a very dangerous disease caused by Mycobacterium tuberculosis. In the year of 2019, TB has caused 1.4 million deaths, making TB one of the top 10 causes of death worldwide. Indonesia is ranked having the second highest TB burden in the world and is striving to eliminate it by 2030. Kalanchoe Pinnata is a plant found in Indonesia of potential with lots of active compounds co…
Tuberculosis is a disease caused by Mycobacterium tuberculosis which mainly attacks the lung but could also cause disease in other organs such as lymphatic system, bone, skin and liver. According to WHO, Indonesia is ranked second in total tuberculosis per year in the w orld. C urrently tuberculosis is handled in Indonesia with medication regimen to cure the disease and BCG vaccination in child…