The COVID−19 pandemic has been going on for three years, and research on preventive and curative measures is continuously being made. Belonging to the same coronavirus family, human common cold coronaviruses (CCCs) like 229E, NL63, HKU1, and OC43 have been around for decades. However, unlike SARS−CoV−2, they do not manifest serious signs and symptoms. Reports on T−cell cross−reactivit…
This study aims to generate molecular infectious clones, incorporating reporter genes (GFP and SfCherry), for flaviviruses and noroviruses—namely, Kunjin, Zika, and Murine Norovirus (MNV). The objective is to use viral constructs for antiviral compound screening and unravel their mechanisms of action. Employing a diverse array of methods, including PCR, CPER, transfection, fluorescence, an…
The second edition of Virology is an accessible introduction designed to enable students to understand the principles of virus structure, replication and genetics. The aim of this book is to help the reader appreciate the relevance of virology in the modern world, including the fields of vaccines, anti-viral drugs and cancer. There is also a chapter on prions. The second edition has been extens…
"Schaechter's Mechanisms of Microbial Disease" provides students with a thorough understanding of microbial agents and the pathophysiology of microbial diseases. The text is universally praised for "telling the story of a pathogen" in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms, rather than forcing students to memorize isolated facts by rot…
Focuses on concepts and principles to present a comprehensive treatment from molecular biology to pathogenesis and control of viral infections. Illustrates why and how animal viruses are studied and demonstrates how the knowledge gained from such model viruses can be used to study viral systems that are still relatively unknown. Provides a thorough introduction to principles of viral pathogen…