Alzheimer’s disease (AD) is a chronic neurodegenerative disease affecting cognition and memory. The exact cause of AD remains unclear, but two primary theories have been suggested to explain its cause: the cholinergic and amyloid hypothesis. The extracellular deposition of amyloid-beta (Aβ) and intracellular accumulation of phosphorylated tau protein called neurofibrillary tangles (NFTs) …
Cognition is an individual’s ability to learn, solve, and appropriately use stored information. Cognitive deficits can manifest in various ways and are commonly caused mainly by age, and other health conditions such as neurodegenerative diseases as well as side effects from certain drugs. Currently, natural supplements using herbal plants have been investigated as cognitive enhancers and b…
"Alzheimer’s Disease (AD) is most common form of dementia and a neurodegenerative disease characterized by significant decline in cognitive ability that interferes with daily activities. This disease is characterized by accumulation of amyloid-β, NFTs, and oxidative stress in the brain of AD patient that leads to inflammation and neurotoxicity. Around 50 million people worldwide suffer from …