Alzheimer’s disease (AD) is a chronic neurodegenerative disease affecting cognition and memory. The exact cause of AD remains unclear, but two primary theories have been suggested to explain its cause: the cholinergic and amyloid hypothesis. The extracellular deposition of amyloid-beta (Aβ) and intracellular accumulation of phosphorylated tau protein called neurofibrillary tangles (NFTs) …
Numerous health benefits of medicinal plants are attributed to the abundance of phytochemicals. Among these plants is Elaeocarpus grandiflorus, an endemic tree native to Southeast Asia. The locals utilize its leaves, fruit, endocarp, and bark to treat a variety of illnesses, such as acute intestinal inflammation, diarrhea, and urinary tract infections. This study aims to evaluate and quantif…
Coriandrum sativum leaves extract was made in dosage form of effervescent granules which were expected to have an ability in treating Alzheimer ’s disease. It is essential to obtain the optimal formulation in order to achieve the most efficient medications. Therefore, this study aimed to formulate effervescent granules containing coriander extract and evaluate the physicochemical characte…
Wounds are defined as the occurrence of damage and/or disruption of the skin integrity, mucous membrane, and also organ tissue which can disrupt the protective function of the epidermal tissue. Binahong (Anredera cordifolia (Ten.) Steenis.) is one example of a plant that can and has been used empirically to heal external wounds due to its bioactive compounds. However, there are some limitat…
"Alzheimer’s Disease (AD) is most common form of dementia and a neurodegenerative disease characterized by significant decline in cognitive ability that interferes with daily activities. This disease is characterized by accumulation of amyloid-β, NFTs, and oxidative stress in the brain of AD patient that leads to inflammation and neurotoxicity. Around 50 million people worldwide suffer from …