Marine Streptomyces BLH 3-7 had been isolated from Bitung Sea, Sulawesi, as bacteria capable of hydrolyzing agar. To optimize the agarase activity from the bacteria, selection of the best temperature for culture condition and modifying the carbon, nitrogen, and mineral range of concentration in the media (e.g., maltose, (NH4 Methodology (RSM) was conducted. The temperature of 37 activity as the…