The Medial Habenula-Interpeduncular Nucleus (MHb-IPN) pathway is an emerging with recently discovered roles in fear memory expression. As ongoing research revealed the asymmetric functions of this pathway in mammals, questions were asked regarding the developmental origins of this asymmetry, particularly its relation to the visceral asymmetry. This study set out to investigate the lateral a…
The medial habenula (MHb) is the less explored subregion of the emerging brain structure, Habenula (Hb) with roles in fear memory expression, anxiety, and addiction. At the neuron terminals where MHb neurons project to, the interpeduncular nucleus (IPN), vesicular neurotransmitter release is triggered by the influx of calcium ions via Ca v2.3 calcium channels, and robustly potentiated by GABAB …