Pancreatic cancer (PC) is a highly aggressive malignancy with limited treatment options and poor prognosis. Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) protein is abundantly expressed in PC cells and has been linked to tumor growth and metastasis. This research intends to provide insights into the cytotoxic effect of the CEACAM6-mediated targeted therapy using anti-CEACA…
Pancreatic Cancer (PaCa) is the 5th leading cause of cancer-related death in the UK. Understanding the signalling behind PaCa development is essential to create novel treatment for PaCa. RAMPs are family of single transmembrane domain proteins. The interaction between RAMP and GPCR give rise to AM receptor complex. AM is a hormone that has been shown to promote progression of various tumou…