Investigation of The Effectiveness of P-compound Towards The Inhibition of In…

Edition

-

ISBN/ISSN

EP082

Collation

35 p. : ill. ; 30 cm.

Series Title

-

Call Number

EP BM-006

"Construction of Mini-genome System for both Rabies virus Laboratory Strain a…

Rabies virus (RABV) causes a zoonotic disease known as rabies that affects humans and mammals. With a genome length of 12 kb, RABV is classified as a non-segmented, negative-stranded RNA virus that encodes five different structural proteins. The nucleoprotein (N), phosphoprotein (P), and large RNA polymerase protein (L) forms ribonucleoprotein (RNP); together with the viral genome it serves …

Investigating the Role of HDXX as a Novel DNA Damage Response Protein in Colo…

Colorectal cancer (CRC) ranks third in cancer incidence and cancer-related mortalities worldwide. The transformation of normal colon and rectal cells to malignant adenocarcinomas due to unrepaired DNA damage which leads to oncogenic mutations. These mutations also increase the frequency of DNA damage, leading to endogenous replication stress (RS). This introduces an opportunity to induce sy…

Role of Fatty Acid Synthesis Towards HCV Replication

Hepatitis C Virus (HCV) remains a significant global health threat, contributing to chronic infections and hepatic complications, including hepatic steatosis and hepatocellular carcinoma (HCC). This study investigates the intricate relationship between HCV and fatty acid metabolism, focusing on lipid droplet accumulation and the impact of HCV on fatty acid synthesis genes. Utilizing an HCV-infe…

Investigation Of Virus-host Interaction Upon Rna Virus Infection

The overarching goal of this project is to comprehend the intricate dynamics of RNA viruses, specifically influenza A viruses, enteroviruses, and coronaviruses, which pose significant health threats. The focus lies in exploring hostŸvirus interactions, particularly the roles of host components in various stages of viral RNA replication, aiming to identify potential targets for antiviral interv…