Investigation of Atopic Dermatitis-related Gene Expression Levels of TNF-?- &…

Atopic dermatitis (AD) is a multifactorial chronic relapsing inflammatory skin disease characterized by flares of pruritic lesions, rashes and lichenification. Skin barrier and immune barrier dysfunction, grouped with genetic predisposition all contribute to the development of AD. Available medications with the purpose of mitigating symptoms and exacerbations provide surface-level therapeuti…

The Use of Keratin-Biocellulose Black Tamanu Oil Hydrogels as A Novel Wound D…

Diabetes mellitus is a global health issue that is gaining traction in our healthcare system which leads to impaired wound healing and results in chronic ulcers, these increases the risk of amputation and disease mortality rate by 50-59% in 2020. Therefore, better inventions to treat diabetic ulcers are required. A bio-cellulose hydrogel is a form of wound dressing that can aid in protecting t…

In-Vivo Study Of Wound Healing And Antimicrobial Properties Of Biocellulose I…

Chronic diabec wound is a common complicaon in diabetes mellitus which is caused by a prolonged wound-healing process from a persistent inflammaon phase. Thus, proper wound treatment is needed to promote wound healing and protect the wound from infecon. Biocellulose (BC) as wound dressing provides a moist environment to protect skin and pr…

In Vivo Wound healing and Antibacterial Activity Study of Black Tamanu Kerati…

Wound healing is a process that naturally takes place when the body is injured, comprising four phases: hemostasis, inflammaon, proliferaon, and remodeling. Proper wound care is crucial to prevent infecon and complicaons that can impact the paent's quality of life, and to accelerate the healing process. Biocellulose (BC), a bacterial-derived …

INVESTIGATING THE EFFECT OF Calophyllum Inophyllum ETHANOLIC EXTRACT ON THE G…

Atopic dermatitis is a chronic skin disease that affects 20% of children aged three to six months and 3% of adults worldwide. Despite its prevalence, the exact cause of the disease remains unclear due to its complexity of the disease. Many available drugs in the market for treating AD focus on preventing the disease from worsening, such as managing skin infection, hydration, inflammation, a…

Production and Characterization of Biocellulose and Keratin as a Diabetic Wou…

Skin wound healing is a biological course of events where a series of molecular and cellular events works together to restore the damaged tissue in four phases. Several factors could interfere with the completion of those phases, causing delayed and abnormal wounds which may lead to ulcers. Commonly, the formation of ulcers is associated with type II diabetes mellitus (T2DM) disorder which …

THE STUDY OF TAMANU (Calophyllum inophyllum) OIL EFFECTS ON ATOPIC DERMATITIS…

Atopic dermatitis (AD) is a common chronic inflammatory skin disease affecting almost 2.4% of the population worldwide. Due to the complex interactions of genetic, environmental, and immunological variables, AD is still incurable as the knowledge of this complex disease is still limited. Moreover, current available treatments can only treat its symptoms and stop them from getting worse. The…

In Vivo Diabetic Wound Healing Evaluation of Biocellulose Green Tamanu Hydrogels

Diabetic foot ulcers are the most common complications in persons with poorly controlled diabetes (DM). This syndrome can be caused by inadequate glycemic control, underlying neuropathy, a slow and progressive circulation disorder (PVD), or terrible foot care. Around the world, 9.1 to 26.1 million suffer from diabetic foot ulcers. Usually, people at any age are commonly suffering from diabet…

In Vivo Diabetic Wound Healing Evaluation of Biocellulose Black Tamanu Oil Hy…

Diabetes mellitus is one of the most prevalent diseases; with an estimated 422 million cases worldwide. A general cause of blindness, heart attacks, stroke, kidney failure and amputation of the lower limbs. Diabetes mellitus is one of the major causes of impaired wound healing. Furthermore, open wounds in diabetic individuals can be life threatening as it can act as a way for bacteria to ent…

In vivo Diabetic Wound Healing Evaluation of KBC Green Tamanu Oil Hydrogels

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BM 22-035

In vitro comparative analysis of ethanolic tamanu (Calophyllum inophyllum) ex…

Atopic Dermatitis or AD has been introduced since the early 1800s as the most common type of eczema. The reason for the emergence of this disease is still unclear, but researchers believe that inflammation plays an important role in the development of the disease and its severity. Although many drugs are available to lessen the symptoms of the disease, they are known to exhibit serious side eff…

Antimicrobial Activity of Tamanu Seed Extract and its Effect On Biofilm Forma…

Calophyllum inophyllum or more commonly known as “Tamanu” in French Polynesia or “Nyamplung” in Indonesia, is one of the traditional medicine used in treating skin diseases as well as other cosmetic uses, with one of the most common diseases to be treated being atopic dermatitis. Exacerbations of the disease is generally caused by the attachment and growth of biofilm of Staphylococcus a…

DEVELOPMENT OF NOVEL KERATIN-CONTAINING MATRICES FOR WOUND HEALING APPLICATION

"Wounds are a rising health problem and may become non-healing wounds that require more complicated wound management. In wound management, wound dressing is one of the pillars of treatment in chronic wounds. There are currently many wound dressings, but each type has its own unique and there is no single ideal dressing for all wound types. An ideal wound dressing should promote moist wound envi…