Fungi, particularly medicinal mushrooms, have been extensively harvested for their natural compounds for alternative medicine because they provide benefits with little to no adverse effects. FIPs, or fungal immunomodulatory proteins, are one that have been extensively studied for their immunomodulatory activities to promote lymphocyte production and subsequently enhance cytokine production. FIP…
Background: FIP-Lrh is a fungal immunomodulatory protein from Tiger Milk Mushroom with immunomodulatory and cytotoxic properties. Its biological properties can be further elucidated with the availability of a crystal structure. However, crystal structures from only four FIPs have been reported so far. As such, previous study at UCSI and MGVI on rFIP-Lrh crystallisation under two conditions …