A healthy and moisturized skin is the result of a healthy and functioning barrier function. The barrier function mainly consists of the CE layer of the epidermis, which is formed by the cross-linking of FLG, IVL, and LOR genes that are catalyzed by TGM-1 gene. However, due to many factors, the moisture and water content in the skin may be altered; thus, resulting in dry skin. The usage of moist…