Biofilm formation poses a significant health challenge, playing a role in the pathogenesis of biofilm-associated diseases, including dental caries, a chronic infectious disease with widespread prevalence that significantly impacts oral health. Lactobacillus acidophilus is one of the primary cariogenic microorganisms associated with the progression of dental caries. In order to address this …
Enterohemorrhagic Escherichia coli (EHEC) strains infect millions annually with their ability to colonize the gut and form biofilms contributing to antibiotic resistance. Moreover, CXCL8 (IL-8), TNF-ɑ, and ICAM-1 are genes involved in the inflammatory host response against EHEC infection. Thymus vulgaris, generally known as common thyme, is a traditional medicinal plant with antibacterial …
Hepatocellular carcinoma (HCC) poses a significant challenge in clinical management due to late-stage diagnosis and limited curative interventions. The imperative to develop more efficacious therapeutic approaches for HCC underscores the exploration of oncolytic virotherapy, an innovative treatment modality exhibiting promising antitumor properties. Among potential oncolytic vectors, the measle…
"The human axilla hosts clusters of sweat glands that provide a favorable environment for a large bacterial population. The bacteria-driven process could convert the odorless secretions from the glands into volatile odorous compounds, leading to an unpleasant body odor that may disrupt people’s daily routines. To address this issue, the development of cosmetics like deodorant has the pote…
The main purpose of 3D in vitro models is to impersonate the complexity of real tissue organs. An organoid is a 3D micro-physiological system that can capture the structural and functional characteristics of real organs. Organoid 3D culture is usually cultured from pluripotent stem cells, organ or tissue fragments which are often cultured in hydrogels. The composite of hydrogels has been fo…
Despite being the second leading cause of death, treating cancer is still remarkably challenging. The most commonly used option to treat cancer is chemotherapy regardless of its toxicity not only to cancer cells but also to highly proliferative cells under normal physiological conditions such as hair follicle, bone marrow, and GI tract mucosa, which possibly decrease the patient's quality of li…
An accurate and effective determination of shelf life is crucial to ensure product safety and quality. Accelerated Shelf Life Test (ASLT) is commonly used to predict shelf life faster. However, research regarding ALST for heat-sensitive food including mayonnaise is still limited. This study aims to determine physicochemical and sensorial properties as well as storage temperature which are suita…
Essential Skills for a Medical Teacher is a new book that will serve as a perfect introduction for new teachers to the exciting opportunities facing them, whether they are working in undergraduate, postgraduate or continuing education. It will also be of considerable use to more experienced teachers to review and assess their own practice and gain a new perspective on how best to facilitate the…
In The Vaccine-Friendly Plan, Paul Thomas, M.D., presents his proven approach to building immunity: a new protocol that limits a child’s exposure to aluminum, mercury, and other neurotoxins while building overall good health. Based on the results from his pediatric practice of more than eleven thousand children, as well as data from other credible and scientifically minded medical doctors, Dr…